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What Happens To Your Body The Morning After Smoking Weed

Why you feel blah after eating that brownie.

If you’ve ever been hungover from drinking, then you already know how one night of boozy indulgence can really mess with your mood, well-being, and productivity the next day. And you might have found yourself in a similar sitch the day after eating both halves of a pot brownie. But are weed hangovers real? Some cannabis consumers swear they’ve endured weed-related hangover symptoms, but the experience is far from universal.

If you’ve experienced weird symptoms after staying away from weed for a while, it’s possible that your body has become used to a certain amount of cannabis regularly, and is having difficulty adjusting. “Marijuana withdrawal would be a more appropriate name for [a weeed hangover]” Dr. Scott Braunstein M.D., medical director of healthcare organization Sollis Health, tells Bustle. But a lot of the research on cannabis hangovers is based on people who use it heavily, seven times or more per month, and there’s not a lot of studies about occasional users and how they feel the morning after a big night.

With all of that in mind, here are four commonly reported symptoms of a weed hangover, why they happen, and what you can do to make yourself feel better if you ever experience one.

1. Headaches

Dr. Jordan Tishler M.D., an emergency medicine physician and cannabis specialist, tells Bustle that headaches are more likely to happen while you’re still intoxicated. If your head aches the morning after, you might just be dehydrated. A review of cannabis withdrawal symptoms after heavy use published in Current Addiction Reports in 2018 found that headache was a common symptom, along with chills and shakiness. It’s not really clear why this happens, but it’s possible that it’s to do with brain activity.

“Cannabis binds to neuron receptors, and has a complicated effect on neurotransmitters in the brain,” Dr. Braunstein says. “In chronic users, the brain becomes accustomed to a high level of dopamine.” Dopamine is is a neurotransmitter that plays a big role in sensations of pleasure and reward. Without cannabis, dopamine levels can crash possibly leading to migraine, as one 2017 study published in Neurology found. But it’s not clear if all these puzzle pieces fit together for weed smokers.

The next time you spend your Saturday night getting baked with friends, just be sure you’re drinking plenty of water before, during, and after your cannabis adventures.

2. Brain Fog

Of all the reported symptoms of a “weed hangover,” Dr. Tishler says brain fog and fatigue are the ones he anticipates. “The mechanism is unknown, but I suspect largely related [to] over-stimulation of the CB1 receptors.” These are the main receptors in the brain where cannabis ‘docks’, giving you all its positive effects.

If you smoke regularly and then stop, it could mess with your cognitive abilities. “If marijuana use is discontinued, dopamine levels drop and within about one week, the person can feel a state of anxiety, restlessness, irritability, and even depression,” Dr. Braunstein says. This is why cannabis is seen as psychologically addictive, he says; it gives you a hard emotional time if you go through withdrawal. An overview of cannabis withdrawal in 2017 in Substance Abuse & Rehabilitation found that irritability, restlessness, disturbed mood, depression, and anger could all appear as symptoms.

Other than coffee, good food, and lots of sleep, one way to deal with brain fog is to get out and exercise. Try going for a long walk or run, then cool down with some yoga, and take a hot (or cold) shower afterwards. It may not make your mental fogginess go away completely, but you’ll definitely feel sharper and more alert.

3. Feeling Dehydrated

While studies show that THC can bind itself to the CB1 receptors on our salivary glands, causing them to dry up — aka, dry mouth — Dr. Tishler tells Bustle that dehydration isn’t directly caused by weed. “Dehydration and dry eyes are really not related to cannabis,” he says. If you’re feeling dried out the day after consuming cannabis, it’s probably because you were already dehydrated when you started smoking; or it might be because you didn’t remember to hydrate while you were getting lifted.

Dehydration is pretty easy to avoid. To rehydrate and recover after waking up dehydrated, drink lots of water, and chow down on water-rich fruits and veggies throughout your day.

4. Fatigue

For the most part, weed can actually help some people fall asleep more quickly and stay asleep longer. But if you smoke weed before bed, it’s possible that your high could be messing with the quality of your sleep, ultimately making you feel fatigued the day after you smoke. A study published in 2017 in Psychopharmacology also found that withdrawal from cannabis meant a rise in poor sleep quality, so if you’re a heavy user going without for a while, you might feel a bit more tired.

Naturally, the best way to remedy this hangover symptom is by getting lots of sleep — but if that’s not an option for you due to work or social obligations, then all you can really do is try to treat your body well throughout the day. Drink coffee and water, eat healthy meals, go for a long walk, and consider taking the day off from weed.

The Bottom Line

Dr. Tishler says time is really all any cannabis consumer should need to get back to “normal,” and he advises practicing moderation in all things. “If you’re experiencing weed hangover, likely you’re using too much,” Tishler says.

Also worth remembering? Any product that claims to relieve a pot hangover is likely too good to be true. “There are many products claiming to address this problem, or over-intoxication in general, and I’d advise staying away from them,” Dr. Tishler says. “There is no science yet to suggest that these products are effective, and since they are not regulated at all, there’s no reason to expect that they are safe to use.”

Readers should note that laws governing cannabis, hemp and CBD are evolving, as is information about the efficacy and safety of those substances. As such, the information contained in this post should not be construed as legal or medical advice. Always consult your physician prior to trying any substance or supplement.

Dr. Scott Braunstein M.D.

Dr. Jordan Tishler M.D.

Baron, E. P., Lucas, P., Eades, J., & Hogue, O. (2018). Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort. https://link.springer.com/article/10.1186/s10194-018-0862-2

Bonnet, U., & Preuss, U. W. (2017). The cannabis withdrawal syndrome: current insights. Substance abuse and rehabilitation, 8, 9–37. https://doi.org/10.2147/SAR.S109576

DaSilva, A. F., Nascimento, T. D., Jassar, H., Heffernan, J., Toback, R. L., Lucas, S., DosSantos, M. F., Bellile, E. L., Boonstra, P. S., Taylor, J., Casey, K. L., Koeppe, R. A., Smith, Y. R., & Zubieta, J. K. (2017). Dopamine D2/D3 imbalance during migraine attack and allodynia in vivo. Neurology, 88(17), 1634–1641. https://doi.org/10.1212/WNL.0000000000003861

Jacobus, J., Squeglia, L.M., Escobar, S. et al. Changes in marijuana use symptoms and emotional functioning over 28-days of monitored abstinence in adolescent marijuana users. Psychopharmacology234, 3431–3442 (2017). https://doi.org/10.1007/s00213-017-4725-3

Mathew, R. J., Wilson, W. H., Turkington, T. G., & Coleman, R. E. (1998). Cerebellar activity and disturbed time sense after THC. https://www.ncbi.nlm.nih.gov/pubmed/9666122

Piper, B. J., Beals, M. L., Abess, A. T., Nichols, S. D., Martin, M. W., Cobb, C. M., & DeKeuster, R. M. (2017). Chronic pain patients’ perspectives of medical cannabis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845915/

Prestifilippo, J. P., Fernández-Solari, J., de la Cal, C., Iribarne, M., Suburo, A. M., Rettori, V., … Elverdin, J. C. (2006). Inhibition of salivary secretion by activation of cannabinoid receptors. https://www.ncbi.nlm.nih.gov/pubmed/16946411

Schlienz, N. J., Budney, A. J., Lee, D. C., & Vandrey, R. (2017). Cannabis Withdrawal: A Review of Neurobiological Mechanisms and Sex Differences. Current addiction reports, 4(2), 75–81. https://doi.org/10.1007/s40429-017-0143-1

Stein, M. D. (n.d.). Marijuana use patterns and sleep among community-based young adults. https://www.tandfonline.com/doi/full/10.1080/10550887.2015.1132986

This article was originally published on Oct. 14, 2015

Cannabis withdrawal can feel like many different things, but people commonly report these four symptoms of a weed hangover.

​Why Pot Makes You Paranoid—but Mellows Out Your Buddies

The kind of high you experience depends on a whole bunch of thing

Pot has the overriding perception as the chill-out drug. In fact, almost a third of marijuana users in the U.S. say the main purpose of it is to reduce anxiety or stress, a recent Marist poll found.

But that’s not always the case—in fact, lighting up leaves lots of people paranoid, anxious, and eager for the high to fade. And that can impact those who are not prone to anxiety.

Turns out, there are several factors that can turn a blissfully mellow high into heart-racing paranoia. Here’s what’s going on.

How Pot Gets You High

The high you experience with marijuana actually mimics a process your body has in place to keep anxiety levels in check, says Gregory Gerdeman, Ph.D., an assistant professor of biology at Eckerd College.

This happens through what’s called your endocannabinoid system: One of its functions is to cool down brain synapses that release stimulating neurotransmitters, the primary “go” signal used in brain circuits, says Gerdeman. The endocannabinoid system helps pump the brakes by triggering the release of cannabinoids, chemical compounds that bind to cannabinoid receptors throughout your brain and body. That sends the signal to chill out when we’re wired.

“These receptors are expressed at high levels in areas of the brain that have to do with mood regulation,” says Steven Kinsey, Ph.D., an associate professor of psychology and coordinator of the Behavioral Neuroscience Training Program at West Virginia University. In 2014, a study from Vanderbilt University found that many of these cannabinoid receptors are found in the amygdala, a part of the brain that regulates anxiety and the fight-or-flight response.

Marijuana contains plant-based cannabinoids, too. So when you smoke, vape, or otherwise consume weed, the cannabinoids bind to the same receptors in your body. And that triggers the same relaxing feeling as the release and binding of your body’s own cannabinoids does.

But the truth is, this system doesn’t always go according to plan. There are some factors that can make your hit more likely you to tweak you out than bliss you out.

Higher Levels Of THC Can Make You More Anxious

THC, short for tetrahydrocannabinol, is the psychoactive compound of cannabis, which binds directly to the cannabinoid receptors, says Kinsey. At lower doses this tends to be pretty relaxing. However, the higher the dosage, the more likely it is to spark an anxious reaction.

It’s called a biphasic response, says Gerdeman. As you start to take in small amounts of THC, it can cause a therapeutic effect. But the higher you go, the more likely you are to trigger the opposite effect.

Controlled research here is limited and individual tolerance varies, says Gerdeman, but a recent study provides a benchmark. Researchers from the University of Chicago tested how THC amounts influenced 42 pot users under stressful conditions. Those who took in 7.5 milligrams (mg) of THC felt less stressed by a mock interview than participants given a placebo, and their stress levels went down faster, too. (Here are 19 ways to live a stress-free life.)

But those who took in 12.5 mg of THC reported negative emotions during the mock interview, and were more likely to rate the task as “challenging” or “threatening.”

For reference, Gerdeman says that a joint with about one gram of cannabis flower that has a 15 percent THC content would contain about 150 mg of THC. (Of course, the THC content could be much higher and the joint could be fatter than a single gram, so this isn’t a guarantee.) Some of that THC gets destroyed in the burn, and how much you inhale and your lungs absorb varies widely based on your smoking technique. So if you were to say, smoke a whole joint (not advisable), you’d probably go way beyond that 12.5 mg of THC and straight into the stress zone.

Researchers aren’t exactly clear why more pot leads to the opposite response of lower doses. But like with any drug, it might have to do with differing thresholds, explains Kinsey.

“Some people have a very broad tolerance to the drug, and this is true of sugar and tobacco and alcohol,” he says. “And there can become a point where it’s no longer fun. For example, I enjoy gummy bears. But there are only so many I can eat before I feel sick.”

Tolerance likely depends on a number of factors, including genetics, the makeup of your own neural network in your brain, and how much you’ve used the drug, Kinsey says.

But Another Pot Compound Can Counteract THC

THC is just one piece of the puzzle, though—there are more than 60 other cannabinoids that have been identified in marijuana, including cannabidiol, or CBD. And it seems like CBD actually lessens the stress-promoting consequences of too much THC.

It’s possible that CBD may tone down the receptors that THC binds to by blocking endocannabinoid metabolism, so the effect of the THC may not be as intense—and therefore less likely to steer you into anxiety, says Gerdeman. It’s also possible that CBD also acts on the receptor for serotonin in your brain, which can turn down your stress response.

Overall, lighting up a joint with more THC and less CBD is far more likely to stress you out, says Kinsey.

So if you don’t want to get paranoid, just pick a strain that has more CBD, right?

Well, it’s not so easy. While different strains of cannabis have different levels of THC and CBD, you don’t really know how much of each cannabinoid you’re getting—no matter what your dispensary says.

For example, strains like ACDC, Cannatonic, and Harlequin are touted for their low THC and high CBD content, and pretty much everything else, like OG Kush, is said to be high in THC. But experts say that this is largely, well, BS.

“Just somebody saying, ‘this Blue Dream,’ or ‘this is a heavy sativa,’ or ‘this is a heavy indica’ is practically meaningless these days,” says Gerdeman. “There’s so much misinformation that sometimes breeders don’t even know.”

Researchers have proven this point by purchasing different samples of the same strain in the same city and using advanced testing methods to see what’s really in there, says Dr. Kinsey. Oftentimes, they’re completely different from each other (and different from what the person selling it claims).

Edibles Are Particularly Tricky

Your high depends mainly on the levels of THC and CBD—not necessarily the method you use to consume it, says Kinsey.

However, edibles in particular are much more likely to have high levels of THC in them, which makes them more likely to cause paranoia. Many of them also have very little CBD and other cannabinoids, so you’re losing out on some of the offsetting compounds as well. Plus, ingesting your drugs, rather than smoking, delays the high. Impatient users often consume too many edibles, which can lead to a bad trip.

A reasonable dose of a single-serving edible should generally have about 10 mg of THC, says Gerdeman, which falls in between the calming 7.5 mg and the stress-inducing 12.5 mg pinpointed in the University of Chicago study (so your reaction really will depend on your personal tolerance). But many products that dispensaries sell are much higher, and thus more likely to cause anxiety.

“For most people, if they eat 30 mg of THC in an edible dose, there are going to be a lot of psychoactive side effects that they don’t want,” says Gerdeman. In addition to anxiety and paranoia, Gerdeman says this can also cause sedation, delirium, and dizziness upon standing. Not fun. (Here’s what happened when one man ate too many edibles.)

Even though individual tolerance levels differ, any product with between 30 to 40 mg of THC without much CBD present is pretty likely to stress you out—though the most tolerant and accustomed users may be exempt, says Gerdeman.

Again, though, a package stating a dosage may not be that reliable. Many edibles are mislabeled, says Gerdeman, and there’s pretty much no regulation—plus, if a batch hasn’t been very thoroughly mixed, you may end up with a part that has way more (or less) THC than a label says.

Your Age and Your Mood Can Affect Your High, Too

Your brain changes as you age, and so does your endocannabinoid system, says Gerdeman. For instance, receptor density gets lower as you get age.

“If somebody smoked robustly in their 20s and picked it back up in their 30s, their brain’s endocannabinoid system may not be at the same set point,” says Gerdeman. That’s why you may notice getting paranoid when you smoke now, whereas pot may have mellowed you out when you were in college.

It’s not just you, though—there’s another way time affects your high. Over the past several decades, marijuana has been bred to have way higher levels of THC than it did in the good old days, says Kinsey.

According to Gerdeman, experts say that the percentage of THC in cannabis was about 7 percent in the 70s, while it’s often about 20 percent these days and often much higher. (Remember, as a middle ground, 15 percent THC content in one gram of cannabis flower would shake out to about 150 mg.) However, Gerdeman stresses that these estimates aren’t necessarily that accurate because the old data may not be reliable as what’s out there now.

Even so, if you think you’re smoking the same amount that you used to—say, you always cut yourself off after one joint shared between a handful of buddies—the THC may be off the charts compared to what you used to buy.

What’s more, how you’re feeling can affect your tolerance too. When life is stressing you out, you might be more susceptible to the anxiety-inducing effects of pot. There’s a bit of emotional release that happens when you get high, and if you’re barely controlling your emotions without weed, adding a joint or edible into the mix could give your subconscious mind permission to, well, freak out, says Gerdeman. This isn’t true for everyone, of course—some people find it useful to let go a little bit when they’re dealing with a particularly tough or vulnerable time.

Setting is also important, too, Gerdeman adds: If you’re already super paranoid about where you are or having your wife walk in when you’re smoking up, for example, you may be more likely to feel more paranoid when you’re actually high.

If anxiety hits during your next high, the best thing you can take a time out. Go for a breather, but don’t drive anywhere.

“Your liver will help clear it out, but the more THC you have on board the longer that will take,” Kinsey says. How long are we talking? Depending on how much you consumed and your own body chemistry, it could take a couple hours (or more), says Gerdeman—but it will pass, he assures.

Still, if pot continues to make you feel crappy, that might be a sign to put down the joint. Plus, while the climate around recreational pot use is changing, and it’s now legal in several states, no one knows how it affects your health down the line.

The kind of high you experience depends on a whole bunch of thing