Can CBD oil help with stomach ulcers, and if so, how? Stomach ulcers, also known as gastric ulcers, are a type of peptic ulcer disease. As bothersome as skin ulcers & skin wounds, stomach ulcers, & oral ulcers can be, is medical marijuana a possible solution for your pain? These persistent and open sores discovered in a few areas around your body are no laughing matter.
CBD Oil for Stomach Ulcers – August 2022
Can CBD oil help with stomach ulcers, and if so, how?
Stomach ulcers, also known as gastric ulcers, are a type of peptic ulcer disease. ‘Peptic’ ulcer is the umbrella term for any ulcer affecting the stomach and the small intestines.
The stomach usually produces acid to help with the digestion of food and protect against bacteria and other microbes.
Meanwhile, cells on the inside lining of the stomach and first portion of the small intestine (duodenum) produce a natural mucus barrier to protect the tissues of the body from this acid.
There is usually a balance between the amount of acid that the body makes and the mucus defence barrier – as well as the amount of base produced by the pancreas.
Ulcers may develop if there is an alteration in this balance, allowing the acid to damage the lining of the stomach or duodenum.
Stomach ulcers are characterized by open sores in the lining of the stomach. While small ulcers may not cause noticeable symptoms, larger ones can cause pain and discomfort (1)
Ulcer symptoms are often worse on an empty stomach and at night. Ulcer symptoms include:
- Discomfort or burning pain in the upper abdomen
- Feeling bloated
- Weight loss and lack of appetite
- Dark black stools
CBD for Stomach Ulcers: What The Research Says
There is evidence that cannabinoids like CBD and THC have a positive physiological impact on stomach pathology, including ulcers.
According to research , there is evidence that CB1 receptor stimulation with cannabinoids inhibits gastric acid secretion in humans and experimental animals (2) .
Studies have shown that CBD can decrease gastric acid and increase blood flow to the lining of the stomach.
Researchers of a 2016 study published in Current Neuropharmacology found that direct activation of CB1 receptors by cannabinoids effectively reduces both gastric acid secretion and gastric motor activity and decreases the formation of lesions on the stomach lining (3) .
A study examined how cannabinoids impact the gastrointestinal tract of some species, like the mouse, rat, guinea pig, and humans (4) .
In another study published in Pharmacology Journal, researchers found that delta-9-tetrahydrocannabinol (THC) inhibited ulcer formation in animal models (5) .
Although the studies did not focus on the cannabinoid CBD, the results are still encouraging. The authors believe the endocannabinoid system represents a promising target in the treatment of gastric mucosal lesions, ulceration and inflammation.
CBD for Pain Relief
Prescription medication is not the only reliable scientific solution to treating conditions, such as stomach ulcers.
Chemical-based painkillers have even been known to cause stomach ulcers in the first place.
According to the National Health Service (NHS) of the United Kingdom, taking non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or aspirin, can cause stomach or duodenal ulcers, particularly if these pharmaceuticals are taken for an extended period or at high doses (6) .
Meanwhile, CBD may also help provide effective pain relief from the invasion of stomach ulcers.
Studies have shown that CBD may have promise in helping provide pain relief. CBD may be useful in treating different types of chronic pain (7) .
Chronic pain, particularly neuropathic pain, is a problem that is difficult to treat, according to the author of a study on neuronal mechanisms for neuropathic pain (8) .
CBD for Nausea
Nausea is a feeling or urge to vomit. It can develop for several reasons, including medications, chemotherapy, food poisoning, morning sickness, general anesthesia, and migraines (9) .
Nausea and vomiting both play an essential, defensive role by rejecting the ingestion or digestion of potentially harmful substances.
Cannabis has long been known to prevent or regulate nausea and vomiting from a variety of causes (10) .
The studies demonstrated that primary cannabinoids, tetrahydrocannabinol (THC) and cannabidiol (CBD), have both been useful at regulating vomiting and nausea because they interact with cannabinoid receptor 1 (CBB1) of the endocannabinoid system.
Activating the CB1 receptor suppresses vomiting, as noted in the review published in the journal Psychopharmacology (11) .
Studies have shown that CBD’s effectiveness at producing anti-nausea effects may also be in part of its indirect activation of the 5-HT-1A autoreceptors in the “vomiting center” or “chemoreceptor trigger zone” of the brain stem (12) .
Activation of 5-HT1A heteroreceptors in these areas releases serotonin (13) .
Serotonin is found mostly in the digestive system, although it is also in blood platelets and throughout the central nervous system.
Serotonin is sometimes called “the happy chemical” because it contributes to feelings of well-being and happiness.
CBD’s purported therapeutic benefits may help with symptoms of stomach ulcers. However, more research is needed to validate the results of the studies.
WHO states that CBD “is generally well-tolerated with a good safety profile.” (14) Still, the long-term effects of CBD remain unknown, and the compound may also interact with other pharmaceuticals.
Thus, individuals looking to try CBD for the first time, or intend to use CBD as an adjunct therapy, should first consult with a doctor experienced in cannabis use for advice.
Can Medical Marijuana Help Skin Ulcers, Stomach Ulcers, & Oral Ulcers?
When it comes to ulcers, they can be awful and painful. Regardless of whether you think of oozy and infected wounds or your gut cringes from stomach pain, these persistent and open wounds found in a few places around your body are no joke. Some ulcers simply go away in a few days to a few weeks such is the case with some ulcers found in the mouth. While stomach ulcers may make it difficult to eat, ulcers or open wounds on the skin can lead to infections, gangrene, cancers, and amputations. Thankfully there has been a lot of research into various types of ulcers and how medical cannabis may be able to help in your recovery process.
Cannabis contains over 100 cannabinoids, terpenes , and other natural compounds that have a variety of healing effects in our bodies. The most common cannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) and are highly sought after for their potential effects. Cannabinoids interact with our body through the endocannabinoid system (ECS) . The ECS is a complex system of cannabinoid receptors CB1 and CB2 that interact with fat-based neurotransmitters that our body naturally produces. CB1 receptors are thought to generally affect the central nervous system while CB2 receptors can be found in a variety of tissues and organs. By ingesting cannabis, the cannabinoid receptors are activated and can raise and lower endocannabinoids such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG).
The endocannabinoids in our body are responsible for a variety of essential functions including how we perceive pain, calming inflammation , slowing digestion, and allowing our body to maintain homeostasis. Through medical cannabis, researchers have found that these bodily functions can be improved or changed to help us relieve symptoms of many chronic conditions.
Skin Ulcers and Medical Cannabis
Skin ulcers are no laughing matter and can be much more than long-lasting wounds. They can often be caused by circulation issues where blood flow is reduced or cut-off, mostly in the legs, and sores form. Ulcers on the skin can also be caused by injuries that have not healed properly. Another type of ulcer called decubitus ulcers is caused when people who are ill and have reduced mobility sit on pressure points on their skin too long and sores form. These are also known as bedsores. Fortunately, there is a lot of research that supports the use of medical cannabis for chronic pain , skin wounds, and healing skin inflammation in conditions such as eczema , psoriasis , and acne (23) .
Please check out our page on skin ulcers for more details.
Medical Marijuana and Peptic Ulcers
Peptic ulcers, also known as gastric ulcers, duodenal ulcers, or stomach ulcers are open sores that are found in our stomach or the first part of the small intestine called the duodenum. They are extremely painful and can cause other digestive issues including acid reflux, loss of appetite, possibly gastric cancer, abdominal pain, and nausea . Though doctors used to think the primary cause of peptic ulcers was stress, now they know they are often caused by a type of bacteria called H. Pylori or by overuse of non-steroidal anti-inflammatory drugs (NSAIDs).
Research regarding medical cannabis shows that when THC is used in high concentrations it can slow stomach acid secretions and the digestive tract, which slows gastric emptying (15). They also believe that it can reduce pain and inflammation in the stomach lining as well as damage to this mucosal layer (9). Typically gastric ulcers can be treated with antacids, proton pump inhibitors to control acid production, and antibiotics.
Please check out our page on stomach ulcers for more information.
Oral Ulcers and Cannabis Use
Ulcers in the mouth can be bothersome, but they usually go away quickly. They can be caused by a variety of factors including oral herpes (cold sores), canker sores, head and neck cancers, or irritations in the mouth. Research published in the Journal of Dental Research supports the use of CBD for healing stomach ulcers that are caused by acidic foods or trauma (16). This research also shows that oral spray application of CBD reduces the number of cells that die from inflammatory cascades and accelerates oral ulcer healing.
Please check out our page on oral ulcers for more information.
Note: Veriheal does not intend to give this as professional medical advice. Do not attempt to self-diagnose, or prescribe treatment based on the information provided on this page. Always consult a physician before making any decision on the treatment of a medical condition.
Can CBD Relieve Ulcer?
Ulcers can be excruciating and unpleasant. Whether you imagine oozy and infected wounds or stomach aches, these persistent and open sores discovered in a few areas around your body are no laughing matter. Some ulcers, such as those seen in the mouth, simply disappear in a matter of days or weeks. While stomach ulcers make eating difficult, skin ulcers or open wounds can lead to cancer, infections, gangrene, and amputations. But thankfully, now, various research has been done on different types of ulcers and how medicinal cannabis could aid in your healing.
Cannabis includes approximately 100 cannabinoids, terpenes, and other natural substances with different medicinal properties. The most widely used cannabinoids are 9-tetrahydrocannabinol (THC) and cannabidiol (CBD), both highly sought after for potential benefits. Various Blush CBD products are available in the market like CBD Tincture, Oil, Cream, etc. Through the endocannabinoid system, cannabinoids interact with our bodies (ECS), a complex system of cannabinoid receptors CB1 and CB2, which interact with fat-based neurotransmitters produced by our bodies. CB1 receptors are assumed to influence the central nervous system, but CB2 receptors can be seen in many tissues and organs. Cannabinoid receptors are active when cannabis is consumed, and they can boost or drop endocannabinoids such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG).
Endocannabinoids are responsible for several vital processes in our bodies, including perceiving pain, soothing inflammation, slowing digestion, and maintaining homeostasis. Researchers have discovered that medical cannabis can help us improve or change certain biological functions, which can help us ease the symptoms of many chronic disorders.
Medical cannabis and skin ulcers
Skin ulcers are not to be taken lightly, and they can be much more than long-term wounds. They are frequently caused by circulation problems, in which blood flow is limited or cut off, usually in the legs, resulting in sores. Injuries that have not appropriately healed might also result in skin ulcers.
Decubitus ulcers arise when persons who are unwell and have limited mobility sit on pressure points on their skin for an extended period, causing sores. Bedsores are another name for this condition. Fortunately, there is plenty of evidence that medical cannabis can help with chronic pain , skin sores, and skin inflammation in illnesses including eczema, psoriasis, and acne.
Medical peptic ulcers and marijuana
Peptic ulcers, also known as duodenal ulcers, or stomach ulcers, are open sores that develop in the stomach or the duodenum, the first section of the small intestine. They are excruciatingly uncomfortable and can result in additional digestive problems such as acid reflux, loss of appetite, gastric cancer, abdominal pain, and nausea. Though doctors believed that stress was the primary cause of peptic ulcers, they now know that H. Pylori bacteria or overuse of non-steroidal anti-inflammatory drugs are the most common causes (NSAIDs).
When administered in high doses in medical cannabis, THC has been shown to inhibit stomach acid production and the digestive tract, slowing gastric emptying. They also believe it can help with the stomach lining pain, inflammation, and mucosal layer damage. Antacids, proton pump inhibitors to limit acid production, and other medications commonly treat stomach ulcers.
Cannabis use and oral ulcers
Mouth ulcers can be annoying, but they usually go away fast. They can be caused by various things, such as oral herpes (cold sores), canker sores, head and neck malignancies, or mouth irritations. As per the research published in the Journal of Dental Research, CBD can help repair stomach ulcers caused by acidic meals or trauma (16). This study also found that using CBD as an oral spray lowers the number of cells killed by inflammatory cascades and speeds up the healing of oral ulcers.
Veriheal does not intend for anything to be taken as medical advice. Please do not self-diagnose or prescribe treatment based on the information on this website. Always seek medical advice before making any treatment decisions for a medical issue.
Many people are turning to more natural approaches to treat ulcers, such as diet, over-the-counter medicines, or pharmaceutical medications. Many people are now wondering how CBD (cannabidiol) or a combination of CBD and THC (Tetrahydrocannabinol) can aid in the treatment of ulcers.
Ulcers can affect more than 4 million people in the United States each year; according to Harvard Medical School, 1 in 10 people will develop an ulcer.
Ulcers of various types
Ulcers are classified into different categories based on their location in the body. Peptic ulcers are sores on the stomach, small intestine, or esophagus lining. A gastric ulcer is a peptic ulcer in the stomach. A peptic ulcer develops in the first segment of the small intestine, known as a duodenal ulcer (duodenum). The bottom region of your esophagus is affected by an esophageal ulcer.
What CBD and THC can do for you
The endocannabinoid system contains cannabinoid receptors in our stomachs. The cannabinoids bind to these receptors. The CB1 receptor instructs the stomach to cease manufacturing stomach acid, which helps reduce acid reflux. The antisecretory, antioxidant, anti-inflammatory, and vasodilatory properties of cannabis/cannabinoids protect the stomach mucosa. It was discovered in 1978 that acute and long-term cannabis administration reduced the rate of stomach ulcers in rats subjected to restraint stress.
‘The digestive system includes endogenous cannabinoids (anandamide and 2-arachidonoylglycerol), and cannabinoid CB1 receptors can be detected on myenteric and submucosal neurons,’ according to a 2001 study of cannabinoid gastrointestinal effects. GGI motility, intestinal secretion, and stomach acid secretion are inhibited when CB1 receptors are activated. ‘The intestinal placement of CB1 receptors could provide novel techniques for managing gut problems,’ the study concluded. Cannabis’ muscle relaxant qualities make it effective for treating acid reflux in addition to affecting stomach acid. The sphincters in the stomach relax, which reduces reflux. The CBD inhibits acid output while it interacts with the endocannabinoid system, resulting in physical burn when dealing with acid reflux symptoms.
CBD also has anti-inflammatory qualities , making it an effective treatment for acid reflux sufferers. Cannabis can also help patients relax and reduce tension.
Final thoughts: Choosing the best dosage and delivery methods
Individuals choose different delivery methods. Here are the most frequent:
- Smoking. Smoking cannabis provides the quickest relief, but it comes with the danger of irritating your lungs or throat, as with all forms of smoking.
- Vapourising. Vaping, like smoking, provides quick relief, but it does not expose you to the adverse effects of smoking. If you want to vape CBD and are concerned that: does CBD smell like weed, so be assured, it’s safe to use.
- Tincture. A tincture is an effective treatment for upper digestive diseases since it is absorbed immediately into submucosal tissues upon eating. You can use tinctures as a mouth spray for quick relief. Additionally, cannabis tinctures can be mixed into meals or drinks or taken sublingually for fast symptom alleviation.
- Capsules. Although slower acting, capsules may be preferable if you want a more precise dose. To acquire your THC dose, you can use tinctures, edibles, or sublingual mouth sprays. If the psychoactivity (of THC) bothers you, you can always add CBD to the mix, so 5 mg of THC and 5 mg of CBD three times a day would be a decent place to start.
Robert Haynes did his degree in psychology at the University of Hertfordshire. He is interested in mental health, wellness, and lifestyle.
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