best cannabis for depression

The 8 Best Marijuana Strains For Depression

Owing to the growing adoption of cannabis products by people, the global market is expanding at a lucrative rate. Research suggests that it may help treat various ailments, one of them being depression. The use of marijuana to alleviate symptoms of depression is gaining momentum worldwide as it is a natural alternative to synthetic supplements that may have harmful side effects.

Depression is a common disorder that affects millions of people around the globe. It affects not only your mood and emotions but also your physical health and well-being. Medical marijuana is rich in cannabinoids and terpenes. It contains two prime compounds, THC and CBD, which may have the ability to help people with depression.

Marijuana strains for depression:

Cannabidiol is one of the prominent cannabinoids extracted from marijuana and hemp plants. CBD is available in numerous forms on the market, capsules, and oils being the most convenient. You can get CBD capsules Canada from local stores or online dispensaries.

Different marijuana strains have different effects on your body and mind, the three broad categories being Sativa, indica, and hybrid. It would be best if you chose the strain as per your needs and preference. Being a beginner, it might seem a bit overwhelming, but you can always explore and find what suits you the best. Read on to learn about the eight best marijuana strains for depression.


Harlequin is a Sativa dominant strain with a high Cannabidiol (CBD) to THC ratio of 5:2. These low levels of THC may help ease your fatigue and stress without compromising mental clarity. Moreover, this strain lets you function without the cloudiness and psychoactive high. It thereby balances the effects of both these compounds.

Jack Herer:

Do you have a hard time getting out of bed in the morning because of depression? Jack Herer, a Sativa dominant marijuana strain, originating from the Netherlands, might be the ideal choice for you. Its ability to reduce symptoms of depression and its delightful aftertaste of sweet grapefruit has made it extremely popular among users.

This highly regarded medical strain can motivate you on low days and give you the boost of energy you require to conquer the negative thoughts. Usually used in the morning, this strain can help you remain focused for the entire day. It can particularly aid cancer patients who usually struggle with psychological distress, appetite loss, and nausea.

Granddaddy Purple:

Granddaddy Purple is perhaps the most well known purple cannabis to treat depression. It is one of the most delightful marijuana strains with stunningly vibrant buds with a purple tint, and bright green leaves that blend seamlessly. This strain features an 80% indica to 20% Sativa ratio.

This indica dominant strain is famous for its stress-relieving effects. It will naturally ease your mind by suppressing the unwanted negative thoughts. You can use it at night to get your mind in a calm headspace to sleep better.

Pineapple Express:

The Pineapple Express strain is a cross between Trainwreck and Hawaiin strains and is well known for its fruity aroma with citrus undertones. This Sativa dominant hybrid strain features a 60:40 Sativa indica ratio.

Depression often hampers your productivity at work or elsewhere. Pineapple Express, well-known for treating mood disorders very effectively, may help you feel more energetic. This allows you to be more productive and focused on your work.

Blackberry Kush:

Are you unable to shake off the negative, anxious thoughts troubling your mind? Blackberry Kush, a sweet-smelling indica dominant strain, might be best suited for you. It is a combination of blackberry and Afghani that has beautiful dark purple buds with shades of orange. Because of its 20% THC content, it may help you relax. This strain is wonderful for unwinding after a long day and may help you get the much-required sleep.

In people suffering from persistent depression, the creative and social side takes a backseat. XJ-13, a THC dominant strain, may help you bring back the color in your life. XJ-13, a strain resulting from the cross between Jack Herer and G-13 haze, exudes a strong citrus scent. Its uplifting properties may bring back your creative and imaginative spark .


Cannatonic is a balanced hybrid with CBD to THC ratio being 2:1. This helps alleviate the symptoms of depression without having to endure the strong cerebral effects usually associated with a high THC strain. It induces mental clarity because of which it is the perfect day time option when you need to get work done.

Sour tsunami:

Sour tsunami is easily identifiable by its dense and dark-colored buds and leaves and has a sweet scent. It has slightly higher levels of THC, as compared to Cannatonic. However, it still allows you to be clear-headed, just with the additional benefit of stress relief. This strain is all about uplifting your spirits and improving your mood.

Final thoughts:

Depression can make even the smallest of tasks seem overwhelming and make you feel weighed down. While living with depression might be hard, these marijuana strains are here to help. Your mental well being should be your priority. So, stop contemplating and start exploring these strains and find out which one suits you the best.

Owing to the growing adoption of cannabis products by people, the global market is expanding at a lucrative rate. Research suggests that it may help treat

Best Marijuana Strains for Depression

Home / Blog / Best Marijuana Strains for Depression

Best Marijuana Strains for Depression

Posted by Marijuana Doctors on 10/17/2019 in Medical Marijuana

Updated on January 21, 2020. Medical content reviewed by Dr. Joseph Rosado, MD, M.B.A, Chief Medical Officer

Clinically depressed people lose the ability to enjoy and engage in life, making even the smallest tasks seem overwhelming. Thankfully, certain strains of cannabis medicine can be very effective in treating both depression and anxiety, an associated condition. Even for people who are not clinically depressed, marijuana can help lift and regulate mood.

The mechanism for marijuana’s mood-stabilizing effects isn’t fully understood. What we do know is that marijuana is rich in cannabinoids and terpenes, which offer myriad health benefits ranging from relaxation, to focus, to tension relief, all which can improve mood and affect.

The terpenes caryophyllene and limonene, for example, boost mood and have specific antidepressant properties. Caryophyllene (beta-caryophyllene, or BCP) lifts mood by targeting the endocannabinoid system’s CB 2 receptor.

Limonene’s sweet citrus smell, found in strains like Harlequin, Jack Herer, and Dirty Girl, stimulates the olfactory and endocannabinoid systems, increasing serotonin and dopamine levels in regions of the brain associated with anxiety, depression and obsessive-compulsive disorder (OCD), as shown in lab rats. In a small human study, 9 out of 12 depressed patients treated with limonene showed improved stress hormone levels and immune function, and were able to reduce their antidepressant medication use.

Strains high in CBD–a ratio of 1:1 with THC is generally considered beneficial–are less likely to cause anxiety. There are even specialty strains focused on individual symptoms of depression, such as a loss of appetite, insomnia, or a lack of motivation and interest in hobbies and activities.

Overall though, to treat anxiety and depression, the following famously mood-altering strains are a great place to start:

  • Jack Herer: Cherished for inspiring happiness, creativity, and focus, this sativa is a classic choice for easing anxiety and depression.
  • Harlequin: Features a 1:1 THC-to-CBD ratio, widely viewed as having a calming and therapeutic effect.
  • Girl Scout Cookies (GSC): This numerous Cannabis Cup-winning hybrid offers a strong dose of pain and nausea relief, appetite-boosting powers, and positive vibes.
  • Granddaddy Purple: Like most indicas, this strain can combat pain, stress, insomnia, appetite loss, and tension.
  • Sour Diesel: This sativa is noted for its ability to improve mood, boost energy, and heighten creativity.
  • Lamb’s Bread: Known for its happy, creative, and uplifting effects, this strain can help ease depression by boosting energy and promoting positive introspection.
  • Pineapple Express: This hybrid takes you to your “happy” place with a fruity profile that inspires energy and bliss.
  • Northern Lights: This pure indica strain relieves pain and sleeplessness with a blissful, comfortable euphoria, relaxing muscles and pacifying the mind.
  • Harlequin: This sativa-dominant strain’s high CBD content counteracts THC’s anxiety-producing effects while amplifying its painkilling power.
  • XJ-13: With its uplifting citrusy aroma, this lightweight sativa-dominant hybrid leaves users clear-headed enough for daytime use, while relieving stress and anxiety.
  • Lavender: An indica with a calming, lavender aroma, this strain balances cerebral bliss and physical relaxation.
  • Cannatonic: A sativa that offers a blissed-out feel, without the anxiety associated with THC, alongside CBD to heighten mood and mental clarity.
  • Sour Tsunami: A hybrid with a high CBD content, this strain is a great option for anxiety-prone individuals and those who are particularly sensitive to THC.

All of these strains can help lift the fog of depression by improving mood, easing anxiety, and boosting energy. To try cannabis for depression, seek professional medical advice to ensure you’re using the right strain, and ingestion method, for you.

About the Author

Sarah A Lybrand is a writer specializing in lifestyle, health, finance, cannabis—and fun. She’s written for Bust, Juno, Yahoo, MarketSmiths and Toast Media, among many others.

Marijuana is rich in cannabinoids and terpenes, which offer myriad health benefits ranging from relaxation, focus, and tension relief.